Welcome to Night City! In the aftermath of The Beast's destruction, Eddie must ally with the mysterious Alchemist and embark on a journey to London's East End... a once familiar stomping ground now under siege by meteoric shards of his fallen adversary. As the city warps into a twisted hellscape, a maniacal Killer stalks the streets with ever increasing power and depravity. And only the Mistress of Acacia Avenue knows where to find him.